Ontology highlight
ABSTRACT:
SUBMITTER: Windels EM
PROVIDER: S-EPMC6884588 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Communications biology 20191129
When exposed to lethal doses of antibiotics, bacterial populations are most often not completely eradicated. A small number of phenotypic variants, defined as 'persisters', are refractory to antibiotics and survive treatment. Despite their involvement in relapsing infections, processes determining phenotypic switches from and to the persister state largely remain elusive. This is mainly due to the low frequency of persisters and the lack of reliable persistence markers, both hampering studies of ...[more]