Ontology highlight
ABSTRACT:
SUBMITTER: Vargas JY
PROVIDER: S-EPMC6885744 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Vargas Jessica Y JY Loria Frida F Wu Yuan-Ju YJ Córdova Gonzalo G Nonaka Takashi T Bellow Sebastien S Syan Sylvie S Hasegawa Masato M van Woerden Geeske M GM Trollet Capucine C Zurzolo Chiara C
The EMBO journal 20191018 23
Tunneling nanotubes (TNTs) are actin-based transient tubular connections that allow direct communication between distant cells. TNTs play an important role in several physiological (development, immunity, and tissue regeneration) and pathological (cancer, neurodegeneration, and pathogens transmission) processes. Here, we report that the Wnt/Ca<sup>2+</sup> pathway, an intracellular cascade that is involved in actin cytoskeleton remodeling, has a role in TNT formation and TNT-mediated transfer of ...[more]