Ontology highlight
ABSTRACT:
SUBMITTER: Valent P
PROVIDER: S-EPMC6886439 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Valent Peter P Orazi Attilio A Savona Michael R MR Patnaik Mrinal M MM Onida Francesco F van de Loosdrecht Arjan A AA Haase Detlef D Haferlach Torsten T Elena Chiara C Pleyer Lisa L Kern Wolfgang W Pemovska Tea T Vladimer Gregory I GI Schanz Julie J Keller Alexandra A Lübbert Michael M Lion Thomas T Sotlar Karl K Reiter Andreas A De Witte Theo T Pfeilstöcker Michael M Geissler Klaus K Padron Eric E Deininger Michael M Orfao Alberto A Horny Hans-Peter HP Greenberg Peter L PL Arber Daniel A DA Malcovati Luca L Bennett John M JM
Haematologica 20190502 10
Chronic myelomonocytic leukemia (CMML) is a myeloid neoplasm characterized by dysplasia, abnormal production and accumulation of monocytic cells and an elevated risk of transforming into acute leukemia. Over the past two decades, our knowledge about the pathogenesis and molecular mechanisms in CMML has increased substantially. In parallel, better diagnostic criteria and therapeutic strategies have been developed. However, many questions remain regarding prognostication and optimal therapy. In ad ...[more]