Individual prediction of psychotherapy outcome in posttraumatic stress disorder using neuroimaging data.
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ABSTRACT:
SUBMITTER: Zhutovsky P
PROVIDER: S-EPMC6889413 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Publications
Individual prediction of psychotherapy outcome in posttraumatic stress disorder using neuroimaging data.
Zhutovsky Paul P Thomas Rajat M RM Olff Miranda M van Rooij Sanne J H SJH Kennis Mitzy M van Wingen Guido A GA Geuze Elbert E
Translational psychiatry 20191202 1
Trauma-focused psychotherapy is the first-line treatment for posttraumatic stress disorder (PTSD) but 30-50% of patients do not benefit sufficiently. We investigated whether structural and resting-state functional magnetic resonance imaging (MRI/rs-fMRI) data could distinguish between treatment responders and non-responders on the group and individual level. Forty-four male veterans with PTSD underwent baseline scanning followed by trauma-focused psychotherapy. Voxel-wise gray matter volumes wer ...[more]
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