Ontology highlight
ABSTRACT:
SUBMITTER: Ley D
PROVIDER: S-EPMC6889478 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Scientific reports 20191202 1
The first thousand days of life are a critical time of development in humans during which the risk profile for diseases in later life can be modified. Nevertheless, long-term consequences of early environment on susceptibility to intestinal diseases have not yet been assessed. Using a mouse model of postnatal growth restriction (PNGR), we showed that early life nutrition influences intestinal maturation and gut health in later life. PNGR induced an alteration of the intestinal barrier in pups at ...[more]