A Flexible Portable Glucose Sensor Based on Hierarchical Arrays of Au@Cu(OH)2 Nanograss.

ABSTRACT: Flexible physiological medical devices have gradually spread to the lives of people, especially the elderly. Here, a flexible integrated sensor based on Au nanoparticle modified copper hydroxide nanograss arrays on flexible carbon fiber cloth (Au@Cu(OH)2/CFC) is fabricated by a facile electrochemical method. The sensor possesses ultrahigh sensitivity of 7.35 mA mM-1 cm-2 in the linear concentration range of 0.10 to 3.30 mM and an ultralow detection limit down to 26.97 nM. The fantastic sensing properties can be ascribed to the collective effect of the superior electrochemical catalytic activity of nanograss arrays with dramatically enhanced electrochemically active surface area as well as mass transfer ability when modified with Au and intimate contact between the active material (Au@Cu(OH)2) and current collector (CFC), concurrently supplying good conductivity for electron/ion transport during glucose biosensing. Furthermore, the device also exhibits excellent anti-interference and stability for glucose detection. Owing to the distinguished performances, the novel sensor shows extreme reliability for practical glucose testing in human serum and juice samples. Significantly, these unique properties and the soft structure of silk fabric can provide a promising structure design for a flexible micro-device and a great potential material candidate of electrochemical glucose sensor.

SUBMITTER: Jiang M 

PROVIDER: S-EPMC6891777 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature