Ontology highlight
ABSTRACT:
SUBMITTER: Zhang W
PROVIDER: S-EPMC6892417 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Zhang Weilong W Zhang Ye Y Yang Zuozhen Z Liu Xiaoni X Yang Ping P Wang Jing J Hu Kai K He Xue X Zhang Xiuru X Jing Hongmei H
Cancer gene therapy 20190109 11-12
Multiple myeloma (MM) is one of hematological malignancies, characterized by malignant proliferation of plasma cells. Biomarkers play an important role in evaluating the development and prognosis of MM. Ubiquitin-conjugating enzyme E2T (UBE2T) is served to connect with particular E3 ubiquitin ligase to degraded-related substrates, contributing to DNA repair in the Fanconi anemia pathway. Also, numerous evidences reported that UBE2T is closely related to cell proliferation and carcinogenesis. How ...[more]