Ontology highlight
ABSTRACT:
SUBMITTER: Sato TR
PROVIDER: S-EPMC6892611 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Sato Takashi R TR Itokazu Takahide T Osaki Hironobu H Ohtake Makoto M Yamamoto Tetsuya T Sohya Kazuhiro K Maki Takakuni T Sato Tatsuo K TK
eLife 20191105
Cortical plasticity is fundamental to motor recovery following cortical perturbation. However, it is still unclear how this plasticity is induced at a functional circuit level. Here, we investigated motor recovery and underlying neural plasticity upon optogenetic suppression of a cortical area for eye movement. Using a visually-guided eye movement task in mice, we suppressed a portion of the secondary motor cortex (MOs) that encodes contraversive eye movement. Optogenetic unilateral suppression ...[more]