Ontology highlight
ABSTRACT:
SUBMITTER: Palu RAS
PROVIDER: S-EPMC6893197 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Palu Rebecca A S RAS Ong Elaine E Stevens Kaitlyn K Chung Shani S Owings Katie G KG Goodman Alan G AG Chow Clement Y CY
G3 (Bethesda, Md.) 20191203 12
Apoptosis is the primary cause of degeneration in a number of neuronal, muscular, and metabolic disorders. These diseases are subject to a great deal of phenotypic heterogeneity in patient populations, primarily due to differences in genetic variation between individuals. This creates a barrier to effective diagnosis and treatment. Understanding how genetic variation influences apoptosis could lead to the development of new therapeutics and better personalized treatment approaches. In this study ...[more]