Intra-procedural and delayed bleeding after resection of large colorectal lesions: The SCALP study.

ABSTRACT:

Background and aim

The safety of endoscopic resection of large colorectal lesions (LCLs) (≥20 mm) is clinically relevant. The aim of the present study was to assess the rate of post-resection adverse events (AEs) in a real-life setting.

Patients and methods

In a prospective, multicentre, observational study, data from consecutive resections of LCLs over a 6-month period were collected in 24 centres. Patients were followed up at 15 days from resection for AEs. The primary endpoint was intra-procedural bleeding according to lesion morphology. Secondary endpoints were delayed bleeding and perforation. Patient and polyp characteristics, and polypectomy techniques were analysed with respect to the bleeding events.

Results

In total, 1504 patients (female/male: 633/871, mean

SUBMITTER: Amato A 

PROVIDER: S-EPMC6893999 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature