Ontology highlight
ABSTRACT:
SUBMITTER: Rouquette I
PROVIDER: S-EPMC6894111 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Rouquette Isabelle I Taranchon-Clermont Estelle E Gilhodes Julia J Bluthgen Maria-Virginia MV Perallon Romain R Chalabreysse Lara L De Muret Anne A Hofman Veronique V Marx Alexander A Parrens Marie M Secq Veronique V Thomas de Montpreville Vincent V Galateau-Salle Françoise F Brousset Pierre P Milia Julie J Girard Nicolas N Besse Benjamin B Molina Thierry Jo TJ Mazières Julien J
Biomarker research 20191204
<h4>Background</h4>Immunotherapy is currently under investigation in B3 Thymoma (TB3) and Thymic Carcinoma (TC). PD-L1 expression has been evaluated on a limited number of patients with selected antibodies. We aimed to analyze cohort of TB3 and TC with a panel of antibodies to assess the prevalence of PD-L1 expression, its prognostic value and to set up a reproducible test.<h4>Methods</h4>We retrospectively studied 103 patients samples of FFPE histologically confirmed TB3 (<i>n</i> = 53) and TC ...[more]