Incidence rates of immune-related adverse events and their correlation with response in advanced solid tumours treated with NIVO or NIVO+IPI: a systematic review and meta-analysis.
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ABSTRACT:
SUBMITTER: Xing P
PROVIDER: S-EPMC6894272 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
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Incidence rates of immune-related adverse events and their correlation with response in advanced solid tumours treated with NIVO or NIVO+IPI: a systematic review and meta-analysis.
Xing Puyuan P Zhang Fan F Wang Guoqiang G Xu Yu Y Li Chengcheng C Wang Shouzheng S Guo Yiying Y Cai Shangli S Wang Yan Y Li Junling J
Journal for immunotherapy of cancer 20191204 1
<h4>Background</h4>Deciphering the correlation between immune-related adverse events (irAEs) categorized by organ system class and clinical benefit of immunotherapy is critical for clinical practice. The aim of this study is to investigate the incidence rates of irAEs and their correlations with objective response rate (ORR) in patients with advanced solid tumours treated with nivolumab (NIVO) or nivolumab plus ipilimumab (NIVO+IPI).<h4>Methods</h4>PubMed, Embase and Cochrane library were search ...[more]
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