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AI-powered transmitted light microscopy for functional analysis of live cells.


ABSTRACT: Transmitted light microscopy can readily visualize the morphology of living cells. Here, we introduce artificial-intelligence-powered transmitted light microscopy (AIM) for subcellular structure identification and labeling-free functional analysis of live cells. AIM provides accurate images of subcellular organelles; allows identification of cellular and functional characteristics (cell type, viability, and maturation stage); and facilitates live cell tracking and multimodality analysis of immune cells in their native form without labeling.

SUBMITTER: Kim D 

PROVIDER: S-EPMC6895055 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

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AI-powered transmitted light microscopy for functional analysis of live cells.

Kim Dongyoung D   Min Yoohong Y   Oh Jung Min JM   Cho Yoon-Kyoung YK  

Scientific reports 20191205 1


Transmitted light microscopy can readily visualize the morphology of living cells. Here, we introduce artificial-intelligence-powered transmitted light microscopy (AIM) for subcellular structure identification and labeling-free functional analysis of live cells. AIM provides accurate images of subcellular organelles; allows identification of cellular and functional characteristics (cell type, viability, and maturation stage); and facilitates live cell tracking and multimodality analysis of immun  ...[more]

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