Different distant metastasis patterns based on tumor size could be found in extensive-stage small cell lung cancer patients: a large, population-based SEER study.

ABSTRACT:

Background

Small-cell lung cancer (SCLC) is a malignant cancer with the ability to metastasize quickly. The relationship between tumor size and the distant metastasis patterns of Extensive-Stage Small Cell Lung Cancer (ES-SCLC) has not been reported.

Objectives

The aim of this study was to determine the different distant metastasis patterns as they related to tumor size in ES-SCLC.

Patients and methods

We used Surveillance, Epidemiology, and End Results (SEER) population-based data collected from 2010 through 2013 to identify 11058 ES-SCLC patients with definite evidence of distant metastases. Multivariate logistic regression analysis was used to demonstrate the association between tumor size and distant metastasis patterns including bone, liver, brain, and lung metas

SUBMITTER: Li J 

PROVIDER: S-EPMC6896937 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature