Ontology highlight
ABSTRACT:
SUBMITTER: Cipriani F
PROVIDER: S-EPMC6897338 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Regenerative biomaterials 20190520 6
The aim of this study was to evaluate injectable, <i>in situ</i> cross-linkable elastin-like recombinamers (ELRs) for osteochondral repair. Both the ELR-based hydrogel alone and the ELR-based hydrogel embedded with rabbit mesenchymal stromal cells (rMSCs) were tested for the regeneration of critical subchondral defects in 10 New Zealand rabbits. Thus, cylindrical osteochondral defects were filled with an aqueous solution of ELRs and the animals sacrificed at 4 months for histological and gross e ...[more]