Ontology highlight
ABSTRACT:
SUBMITTER: Pons A
PROVIDER: S-EPMC6899746 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Angewandte Chemie (International ed. in English) 20191022 48
The ability of silicon to stabilize vinyl cationic species leads to a redox arylation of alkynes whereby the stringent limitations of reactivity and regioselectivity of alkyl-substituted alkynes are lifted. This allows the synthesis of a range of α-silyl-α'-arylketones under mild conditions in good to excellent yields and with high functional group tolerance, whereby the silicon moiety in the final products can either be removed for a formal acetone monoarylation transform, or capitalized upon f ...[more]