Ontology highlight
ABSTRACT:
SUBMITTER: Salles G
PROVIDER: S-EPMC6900267 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Salles Gilles G Bachy Emmanuel E Smolej Lukas L Simkovic Martin M Baseggio Lucile L Panovska Anna A Besson Hervé H Healy Nollaig N Garside Jamie J Iraqi Wafae W Diels Joris J Pick-Lauer Corinna C Spacek Martin M Urbanova Renata R Lysak Daniel D Hermans Ruben R Lundbom Jessica J Callet-Bauchu Evelyne E Doubek Michael M
Annals of hematology 20191119 12
After analyzing treatment patterns in chronic lymphocytic leukemia (CLL) (objective 1), we investigated the relative effectiveness of ibrutinib versus other commonly used treatments (objective 2) in patients with treatment-naïve and relapsed/refractory CLL, comparing patient-level data from two randomized registration trials with two real-world databases. Hazard ratios (HR) and 95% confidence intervals (CIs) were estimated using a multivariate Cox proportional hazards model, adjusted for differe ...[more]