Ontology highlight
ABSTRACT:
SUBMITTER: Abreu GM
PROVIDER: S-EPMC6900366 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Abreu Gabriella de Medeiros GM Tarantino Roberta Magalhães RM Cabello Pedro Hernan PH Zembrzuski Verônica Marques VM da Fonseca Ana Carolina Proença ACP Rodacki Melanie M Zajdenverg Lenita L Campos Junior Mário M
Molecular genetics & genomic medicine 20191002 12
<h4>Background</h4>MODY-NEUROD1 is a rare form of monogenic diabetes caused by mutations in Neuronal differentiation 1 (NEUROD1). Until now, only a few cases of MODY-NEUROD1 have been reported worldwide and the real contribution of mutations in NEUROD1 in monogenic diabetes and its clinical impact remain unclear.<h4>Methods</h4>Genomic DNA was isolated from peripheral blood lymphocytes of 25 unrelated Brazilians patients with clinical characteristics suggestive of monogenic diabetes and the scre ...[more]