Ontology highlight
ABSTRACT:
SUBMITTER: Feola AJ
PROVIDER: S-EPMC6900868 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Feola Andrew J AJ Fu Jieming J Allen Rachael R Yang Victoria V Campbell Ian C IC Ottensmeyer Amy A Ethier C Ross CR Pardue Machelle M
Experimental eye research 20190618
Glaucoma is the leading cause of irreversible blindness worldwide. Recently, estrogen deficiencies caused by early menopause, alterations in estrogen signaling via mutations in estrogen receptors, and polymorphisms along estrogen metabolic pathways have all been linked to an increased risk of developing glaucoma. Here, we examined how menopause and age impact visual function and retinal structure in an experimental model of glaucoma. Young (3-4 months) and aged (9-10 months) female Brown Norway ...[more]