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Dosimetric factors associated with long-term patient-reported outcomes after definitive radiotherapy of patients with head and neck cancer.

ABSTRACT: BACKGROUND:The aim of this study was to explore the relationships between dosimetric parameters of organs at risk and patient-reported outcomes (PRO) after radiotherapy of patients with head and neck cancer. METHODS:PRO data of 53 patients with head and neck cancer treated with radiotherapy were prospectively collected. These data concerned health-related quality of life (HRQOL) and were collected using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (QLQ-C30) and head and neck cancer module (QLQ-H&N35). Patients were divided into "severe-deterioration" and "mild-deterioration" groups on the basis of degree of deterioration HRQOL >?6?months after completing treatment. The relationships between HRQOL deteriorations and patient-related or dosimetry-related factors were evaluated. P?

SUBMITTER: Hayakawa T 

PROVIDER: S-EPMC6902539 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

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Dosimetric factors associated with long-term patient-reported outcomes after definitive radiotherapy of patients with head and neck cancer.

Hayakawa Toyokazu T   Kawakami Shogo S   Soda Itaru I   Kainuma Takuro T   Nozawa Marika M   Sekiguchi Akane A   Miyamoto Shunsuke S   Yamashita Taku T   Ishiyama Hiromichi H  

Radiation oncology (London, England) 20191209 1

<h4>Background</h4>The aim of this study was to explore the relationships between dosimetric parameters of organs at risk and patient-reported outcomes (PRO) after radiotherapy of patients with head and neck cancer.<h4>Methods</h4>PRO data of 53 patients with head and neck cancer treated with radiotherapy were prospectively collected. These data concerned health-related quality of life (HRQOL) and were collected using the European Organization for Research and Treatment of Cancer Quality of Life  ...[more]

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