Ontology highlight
ABSTRACT:
SUBMITTER: El Charif O
PROVIDER: S-EPMC6903403 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
El Charif Omar O Mapes Brandon B Trendowski Matthew R MR Wheeler Heather E HE Wing Claudia C Dinh Paul C PC Frisina Robert D RD Feldman Darren R DR Hamilton Robert J RJ Vaughn David J DJ Fung Chunkit C Kollmannsberger Christian C Mushiroda Taisei T Kubo Michiaki M Gamazon Eric R ER Cox Nancy J NJ Huddart Robert R Ardeshir-Rouhani-Fard Shirin S Monahan Patrick P Fossa Sophie D SD Einhorn Lawrence H LH Travis Lois B LB Dolan M Eileen ME
Clinical cancer research : an official journal of the American Association for Cancer Research 20190405 13
<h4>Purpose</h4>Cisplatin, a commonly used chemotherapeutic, results in tinnitus, the phantom perception of sound. Our purpose was to identify the clinical and genetic determinants of tinnitus among testicular cancer survivors (TCS) following cisplatin-based chemotherapy.<h4>Experimental design</h4>TCS (<i>n</i> = 762) were dichotomized to cases (moderate/severe tinnitus; <i>n</i> = 154) and controls (none; <i>n</i> = 608). Logistic regression was used to evaluate associations with comorbidities ...[more]