Ontology highlight
ABSTRACT:
SUBMITTER: Lee SC
PROVIDER: S-EPMC6904479 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Scientific reports 20191210 1
The E. coli membrane protein ZipA, binds to the tubulin homologue FtsZ, in the early stage of cell division. We isolated ZipA in a Styrene Maleic Acid lipid particle (SMALP) preserving its position and integrity with native E. coli membrane lipids. Direct binding of ZipA to FtsZ is demonstrated, including FtsZ fibre bundles decorated with ZipA. Using Cryo-Electron Microscopy, small-angle X-ray and neutron scattering, we determine the encapsulated-ZipA structure in isolation, and in complex with ...[more]