Ontology highlight
ABSTRACT:
SUBMITTER: Shukla AM
PROVIDER: S-EPMC6905642 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Shukla Ashutosh M AM Wagle Shukla Aparna A
Drugs in context 20191125
Several experimental and clinical studies have transformed the traditional antimalarial role of chloroquine (CHQ) and related structural analogues to potent therapeutic agents for a host of nonmalarial indications. The expanding clinical applicability for these drugs includes rheumatological and cardiovascular disorders (CVD), chronic kidney disease (CKD), oncology, and a variety of nonmalarial infections. These clinical advancements are primarily related to pleiotropic pharmacological actions o ...[more]