Ontology highlight
ABSTRACT:
SUBMITTER: Lahrouchi N
PROVIDER: S-EPMC6906523 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Lahrouchi Najim N Raju Hariharan H Lodder Elisabeth M EM Papatheodorou Stathis S Miles Chris C Ware James S JS Papadakis Michael M Tadros Rafik R Cole Della D Skinner Jonathan R JR Crawford Jackie J Love Donald R DR Pua Chee J CJ Soh Bee Y BY Bhalshankar Jaydutt D JD Govind Risha R Tfelt-Hansen Jacob J Winkel Bo G BG van der Werf Christian C Wijeyeratne Yanushi D YD Mellor Greg G Till Janice J Cohen Marta M Tome-Esteban Maria M Sharma Sanjay S Wilde Arthur A M AAM Cook Stuart A SA Sheppard Mary N MN Bezzina Connie R CR Behr Elijah R ER
European journal of human genetics : EJHG 20190918 1
Sudden cardiac death (SCD) is often associated with structural abnormalities of the heart during autopsy. This study sought to compare the diagnostic yield of postmortem genetic testing in (1) cases with structural findings of uncertain significance at autopsy to (2) cases with autopsy findings diagnostic of cardiomyopathy. We evaluated 57 SCD cases with structural findings at cardiac autopsy. Next-generation sequencing using a panel of 77 primary electrical disorder and cardiomyopathy genes was ...[more]