Ontology highlight
ABSTRACT:
SUBMITTER: Ma RM
PROVIDER: S-EPMC6906798 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Ma Rui-Min RM Yang Fan F Huang Du-Ping DP Zheng Min M Wang Yi-Luan YL
Disease markers 20191121
<h4>Aim</h4>To investigate the mRNA expression and clinical significance of structural maintenance of chromosomes protein 4 (<i>SMC4</i>) in breast cancer.<h4>Methods</h4>A total of 23 paired samples were sequenced, and data from the Cancer Genome Atlas were analyzed.<h4>Results</h4><i>SMC4</i> mRNA level was significantly upregulated in breast cancer tissues (<i>P</i> < 0.001). Patients with high mRNA expression of <i>SMC4</i> had significantly poor survival (<i>P</i> = 0.012). Subgroup analyse ...[more]