Unknown

Dataset Information

0

Saline-push improves rubidium-82 PET image quality.


ABSTRACT: INTRODUCTION:Rubidium-82 (82Rb) PET is used widely for myocardial perfusion imaging. The purpose of this study was to investigate if an additional saline-push following the 82Rb elution improves PET image quality. METHODS:82Rb PET scans were acquired with and without 26 mL saline-push in six patients as part of a clinical quality improvement program. Dynamic images were analyzed to measure the total activity delivered to the superior vena cava (SVC) and retained in the left ventricle (LV) myocardium. Tracer uptake images were used to measure blood background coefficient-of-variation (COV), myocardium-to-blood signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) to assess image quality. RESULTS:Similar eluted activity was measured with/without the saline-push (830 vs 795 MBq; P?=?0.24). The activity delivered to the heart and retained in the myocardium was consistently increased more than twofold (SVC: + 114% and LV: + 104%; P?

SUBMITTER: Renaud JM 

PROVIDER: S-EPMC6908549 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

altmetric image

Publications

Saline-push improves rubidium-82 PET image quality.

Renaud Jennifer M JM   Wu Kai Yi KY   Gardner Kimberly K   Aung May M   Beanlands Rob S B RSB   deKemp Robert A RA  

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 20180327 6


<h4>Introduction</h4>Rubidium-82 (<sup>82</sup>Rb) PET is used widely for myocardial perfusion imaging. The purpose of this study was to investigate if an additional saline-push following the <sup>82</sup>Rb elution improves PET image quality.<h4>Methods</h4><sup>82</sup>Rb PET scans were acquired with and without 26 mL saline-push in six patients as part of a clinical quality improvement program. Dynamic images were analyzed to measure the total activity delivered to the superior vena cava (SVC  ...[more]

Similar Datasets

| S-EPMC8873116 | biostudies-literature
| S-EPMC6517336 | biostudies-literature
| S-EPMC9706837 | biostudies-literature
| S-EPMC10371904 | biostudies-literature
| S-EPMC9345838 | biostudies-literature
| S-EPMC7599151 | biostudies-literature
| S-EPMC6517358 | biostudies-literature
| S-EPMC9834126 | biostudies-literature
| S-EPMC6504625 | biostudies-literature
| S-EPMC8167076 | biostudies-literature