WNT gene polymorphisms and predisposition to apical periodontitis.
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ABSTRACT:
SUBMITTER: de Souza LC
PROVIDER: S-EPMC6908593 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Publications
WNT gene polymorphisms and predisposition to apical periodontitis.
de Souza Letícia Chaves LC Cavalla Franco F Maili Lorena L Garlet Gustavo P GP Vieira Alexandre R AR Silva Renato M RM Letra Ariadne A
Scientific reports 20191212 1
Single nucleotide polymorphisms (SNPs) in WNT genes may impact gene/protein function and contribute to individual predisposition to apical periodontitis (AP). Here, we investigated the association of SNPs in/nearby WNT3, WNT3A, WNT5A, WNT8A, WNT9B and WNT11 genes with AP using a case-control dataset. Cases were defined as individuals with deep caries and AP (n = 188); controls had deep caries and no AP (n = 230). Genotyping was performed using Taqman chemistry in real time PCR. Data analyses was ...[more]
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