Ontology highlight
ABSTRACT:
SUBMITTER: Hong G
PROVIDER: S-EPMC6908598 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Hong Guoju G Han Xiaorui X He Wei W Xu Jiake J Sun Ping P Shen Yingshan Y Wei Qiushi Q Chen Zhenqiu Z
Scientific reports 20191212 1
Serum miRNAs are potential biomarkers for predicting the progress of bone diseases, but little is known about miRNAs in alcohol-induced osteonecrosis of femoral head (AIONFH). This study evaluated disease-prevention value of specific serum miRNA expression profiles in AIONFH. MiRNA PCR Panel was taken to explore specific miRNAs in serum of AIONFH cases. The top differentially miRNAs were further validated by RT-qPCR assay in serum and bone tissues of two independent cohorts. Their biofunction an ...[more]