Ontology highlight
ABSTRACT:
SUBMITTER: Bazazzadegan N
PROVIDER: S-EPMC6908923 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Bazazzadegan Niloofar N Vazehan Raheleh R Fadaee Mahsa M Fattahi Zohreh Z Abolhassani Ayda A Parsimehr Elham E Kalhor Zahra Z Faraji Zonooz Mehrshid M Ahangari Fatemeh F Dehdahsi Shima S Samiee Farshide F Jamali Payman P Habibi Haleh H Nourizadeh Younes Y Mahdavi Shokouh S Beheshtian Maryam M Kariminejad Ariana A Smith Richard Jh RJ Najmabadi Hossein H
Iranian journal of public health 20191001 10
<h4>Background</h4>Diagnosis of hereditary hearing loss (HHL) as a heterogeneous disorder is very important especially in countries with high rates of consanguinity where the autosomal recessive pattern of inheritance is prevalent. Techniques such as next-generation sequencing, a comprehensive genetic test using targeted genomic enrichment and massively parallel sequencing (TGE + MPS), have made the diagnosis more cost-effective. The aim of this study was to determine HHL variants with comprehen ...[more]