Ontology highlight
ABSTRACT:
SUBMITTER: Huang J
PROVIDER: S-EPMC6909274 | biostudies-literature | 2019 Oct-Dec
REPOSITORIES: biostudies-literature
Huang Jinfeng J Wang Qi Q Hu Yingchun Y Qi Zhenhua Z Lin Zhongwu Z Ying Wantao W Zhou Meijuan M
Dose-response : a publication of International Hormesis Society 20191001 4
In response to large-scale radiological incidents, rapid, accurate, and early triage biodosimeters are urgently required. In this study, we investigated candidate radiation-responsive biomarkers using proteomics approaches in mouse models. A total of 452 dysregulated proteins were identified in the serum samples of mice exposed to 0, 2, 5.5, 7, and 8 Gy at 6, 24, and 72 hours postirradiation. Ninety-eight proteins, including 46 at 6 hours, 36 at 24 hours, and 36 at 72 hours, were identified as r ...[more]