Ontology highlight
ABSTRACT:
SUBMITTER: Cheedarla N
PROVIDER: S-EPMC6909397 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Cheedarla Narayanaiah N Sundaramurthi Jagadish Chandrabose JC Hemalatha Babu B Anangi Brahmaiah B Nesakumar Manohar M Ashokkumar Manickam M Vidya Vijayan K K KK Tripathy Srikanth Prasad SP Swaminathan Soumya S Vaniambadi S Kalyanaraman SK Ramanathan D Vadakkupattu DV Hanna Luke Elizabeth LE
AIDS research and human retroviruses 20181220 2
Several broadly neutralizing antibodies (bNAbs) that can target HIV strains with large degrees of variability have recently been identified. However, efforts to induce synthesis of such bNAbs that can protect against HIV infection have not met with much success. Identification of specific epitopes encoded in the HIV-1 envelope (Env) that can direct the host to synthesize bNAbs remains a challenge. In a previous study, we identified 12 antiretroviral therapy-naive HIV-1-infected individuals whose ...[more]