Ontology highlight
ABSTRACT:
SUBMITTER: Kampf C
PROVIDER: S-EPMC6909466 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Kämpf Christoph C Specht Michael M Scholz Alexander A Puppel Sven-Holger SH Doose Gero G Reiche Kristin K Schor Jana J Hackermüller Jörg J
BMC bioinformatics 20191212 1
<h4>Background</h4>A lack of reproducibility has been repeatedly criticized in computational research. High throughput sequencing (HTS) data analysis is a complex multi-step process. For most of the steps a range of bioinformatic tools is available and for most tools manifold parameters need to be set. Due to this complexity, HTS data analysis is particularly prone to reproducibility and consistency issues. We have defined four criteria that in our opinion ensure a minimal degree of reproducible ...[more]