Ontology highlight
ABSTRACT:
SUBMITTER: McKitterick AC
PROVIDER: S-EPMC6910227 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
McKitterick Amelia C AC Hays Stephanie G SG Johura Fatema-Tuz FT Alam Munirul M Seed Kimberley D KD
Cell host & microbe 20191001 4
Phage defense systems are often found on mobile genetic elements (MGEs), where they constitutively defend against invaders or are induced to respond to new assaults. Phage satellites, one type of MGE, are induced during phage infection to promote their own transmission, reducing phage production and protecting their hosts in the process. One such satellite in Vibrio cholerae, phage-inducible chromosomal island-like element (PLE), sabotages the lytic phage ICP1, which triggers PLE excision from t ...[more]