Ontology highlight
ABSTRACT:
SUBMITTER: Chan C
PROVIDER: S-EPMC6911136 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Chan Cindy C Wang Cheng-Wei CW Chen Ching-Hui CH Chen Chi-Huang CH
Journal of assisted reproduction and genetics 20191118 12
<h4>Purpose</h4>To present the first case proposing the use of preimplantation genetic testing for monogeneic disorders for Kallmann syndrome, providing comprehensive care in the genomic era of precision medicine.<h4>Methods</h4>Gonadotropin therapy was used for spermatogenesis, followed by in vitro fertilization by intracytoplasmic sperm injection and embryo transfer. Cross-generational targeted next-generation sequencing was then done for genes known to cause Kallmann syndrome.<h4>Results</h4> ...[more]