Ontology highlight
ABSTRACT:
SUBMITTER: Seo HY
PROVIDER: S-EPMC6912488 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Seo Hye-Young HY Lee So-Hee SH Lee Ji-Ha JH Kang Yu Na YN Choi Young-Keun YK Hwang Jae Seok JS Park Keun-Gyu KG Jang Byoung Kuk BK Kim Mi-Kyung MK
Cells 20191114 11
Clusterin is a glycoprotein that is expressed in most human tissues and found in body fluids. In our previous studies we demonstrated that clusterin has a protective effect against hepatic lipid accumulation and renal fibrosis; however, the role of clusterin in hepatic fibrosis is unknown. Here, we examined whether clusterin had protective effects against hepatic fibrosis using in vitro and in vivo models. Clusterin was upregulated in the livers of human cirrhotic patients and in thioacetamide ( ...[more]