A diffusion-weighted imaging tract-based spatial statistics study of autism spectrum disorder in preschool-aged children.
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ABSTRACT:
SUBMITTER: Andrews DS
PROVIDER: S-EPMC6913008 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Publications
A diffusion-weighted imaging tract-based spatial statistics study of autism spectrum disorder in preschool-aged children.
Andrews Derek Sayre DS Lee Joshua K JK Solomon Marjorie M Rogers Sally J SJ Amaral David G DG Nordahl Christine Wu CW
Journal of neurodevelopmental disorders 20191216 1
<h4>Background</h4>The core symptoms of autism spectrum disorder (ASD) are widely theorized to result from altered brain connectivity. Diffusion-weighted magnetic resonance imaging (DWI) has been a versatile method for investigating underlying microstructural properties of white matter (WM) in ASD. Despite phenotypic and etiological heterogeneity, DWI studies in majority male samples of older children, adolescents, and adults with ASD have largely reported findings of decreased fractional anisot ...[more]
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