A New Class of Homoleptic and Heteroleptic Bis(terpyridine) Iridium(III) Complexes with Strong Photodynamic Therapy Effects.

ABSTRACT: Six homo- or heteroleptic tricationic Ir(R₁-tpy)(R₂-tpy)³⁺ complexes (Ir1-Ir6, R₁/R₂ = Ph, 4'-N(CH₃)₂Ph, pyren-1-yl, or 4'-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}Ph, tpy = 2,2';6',2"-terpyridine) were synthesized and tested for photodynamic therapy (PDT) effects. The ground- and excited-state characteristics of these complexes were studied systematically via spectroscopic methods and quantum chemistry calculations. All complexes possessed intraligand charge transfer (¹ILCT) / metal-to-ligand charge transfer (¹MLCT) dominated transition(s) in their low-energy absorption bands, which red-shifted with the increased electron-releasing strength of the R₁/R₂

SUBMITTER: Liu B 

PROVIDER: S-EPMC6913535 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature