Ontology highlight
ABSTRACT:
SUBMITTER: Lee Y
PROVIDER: S-EPMC6913676 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Lee Yukyeong Y Lee Minseong M Lee Seung-Won SW Choi Na Yong NY Ham Seokbeom S Lee Hye Jeong HJ Ko Kisung K Ko Kinarm K
Animal cells and systems 20191008 6
Spermatogonial stem cells (SSCs) are unipotent adult stem cells, capable of differentiating into sperm cells. SSCs can be cultured <i>in vitro</i> for a long time. SSCs expressing Oct4, a pluripotency marker, and are the only adult cells which pluripotency can be induced under defined culture conditions. However, because 2D culture imposes limitations in cell junction formation, cell shape, metabolism, response to stimuli, and cell interface with medium, mechanistic studies on reprogramming of S ...[more]