Ontology highlight
ABSTRACT:
SUBMITTER: Chen T
PROVIDER: S-EPMC6914919 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Chen Tao T Cui Jingxiang J Ma Lixia L Zeng Yongqing Y Chen Wei W
BioMed research international 20191204
<h4>Objective</h4>The proliferation and differentiation of preadipocytes are regulated by microRNAs (miRNAs), hormones, and other factors. This study aimed to investigate the effects of miR-331-3p on the proliferation and differentiation of preadipocytes in addition to fatty acid metabolism.<h4>Methods</h4>Preadipocytes were transfected with miR-331-3p mimics, miR-NC, or miR-331-3p inhibitor to explore its effect on cell proliferation and fatty acid accumulation. Furthermore, preadipocytes were ...[more]