Ontology highlight
ABSTRACT:
SUBMITTER: Oshchepkova A
PROVIDER: S-EPMC6915531 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Micromachines 20191101 11
Extracellular vesicles provide cell-to-cell communication and have great potential for use as therapeutic carriers. This study was aimed at the development of an extracellular vesicle-based system for nucleic acid delivery. Three types of nanovesicles were assayed as oligonucleotide carriers: mesenchymal stem cell-derived extracellular vesicles and mimics prepared either by cell treatment with cytochalasin B or by vesicle generation from plasma membrane. Nanovesicles were loaded with a DNA oligo ...[more]