Ontology highlight
ABSTRACT:
SUBMITTER: Kreutz C
PROVIDER: S-EPMC6915982 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Genome biology 20191216 1
Insufficient performance of optimization-based approaches for the fitting of mathematical models is still a major bottleneck in systems biology. In this article, the reasons and methodological challenges are summarized as well as their impact in benchmark studies. Important aspects for achieving an increased level of evidence for benchmark results are discussed. Based on general guidelines for benchmarking in computational biology, a collection of tailored guidelines is presented for performing ...[more]