Unknown

Dataset Information

0

Tissue oxygen saturation changes and postoperative complications in cardiac surgery: a prospective observational study.


ABSTRACT: BACKGROUND:Cardiac surgery with extracorporeal circulation (ECC) can induce microvascular dysfunction and tissue hypoperfusion. We hypothesized that the alterations in near-infrared spectroscopy (NIRS)-derived parameters would be associated with post-operative complications in cardiac surgery patients. METHODS:Prospective observational study performed at two University Hospitals. Ninety patients undergoing cardiac surgery with ECC were enrolled. The NIRS sensor was applied on the thenar eminence. A vascular occlusion test (VOT, 3-min ischemia) was performed at baseline (t0), at Intensive Care Unit (ICU) admission (t1), 3 (t2) and 6 (t3) hours later. Baseline tissue oxygen saturation (StO2), oxygen extraction rate and microvascular reactivity indices were calculated. RESULTS:In the first hours after cardiac surgery, StO2 tended to increase (86% [80-89] at T3 versus 82% [79-86] at T0, p?=?ns), while both tissue oxygen extraction and microvascular reactivity tended to decrease, as indicated by increasing occlusion slope (-?8.1%/min [-?11.2 to -?7] at T3 versus -?11.2%/min [-?13.9 to -?7.9] at T0, p?=?ns) and decreasing recovery slope (1.9%/sec [1.1-2.9] at T3 versus 3.1%/sec [2.3-3.9] at T0, p?=?ns). No substantial differences were found in NIRS-derived variables and their changes over time between patients with complications and those without complications. CONCLUSIONS:Peripheral tissue oxygen extraction and microvascular reactivity were reduced during the first hours after cardiac surgery. NIRS-derived parameters were not able to predict complications in this population of cardiac surgery patients.

SUBMITTER: Scolletta S 

PROVIDER: S-EPMC6916088 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

altmetric image

Publications

Tissue oxygen saturation changes and postoperative complications in cardiac surgery: a prospective observational study.

Scolletta Sabino S   Franchi Federico F   Damiani Elisa E   Cennamo Armando A   Domizi Roberta R   Meola Antonio A   Scorcella Claudia C   Vanoli Davide D   Münch Christopher C   Adrario Erica E   Marchetti Luca L   Taccone Fabio Silvio FS   Donati Abele A  

BMC anesthesiology 20191216 1


<h4>Background</h4>Cardiac surgery with extracorporeal circulation (ECC) can induce microvascular dysfunction and tissue hypoperfusion. We hypothesized that the alterations in near-infrared spectroscopy (NIRS)-derived parameters would be associated with post-operative complications in cardiac surgery patients.<h4>Methods</h4>Prospective observational study performed at two University Hospitals. Ninety patients undergoing cardiac surgery with ECC were enrolled. The NIRS sensor was applied on the  ...[more]

Similar Datasets

| S-EPMC8132917 | biostudies-literature
| S-EPMC5435138 | biostudies-literature
| S-EPMC6694555 | biostudies-literature
| S-EPMC10644466 | biostudies-literature
| S-EPMC4419445 | biostudies-literature
| S-EPMC6521399 | biostudies-literature
| S-EPMC6800803 | biostudies-literature
| S-EPMC6378876 | biostudies-literature
| S-EPMC6099367 | biostudies-literature
| S-EPMC7703412 | biostudies-literature