Combining genomics and epidemiology to analyse bi-directional transmission of Mycobacterium bovis in a multi-host system.
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ABSTRACT:
SUBMITTER: Crispell J
PROVIDER: S-EPMC6917503 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
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Combining genomics and epidemiology to analyse bi-directional transmission of <i>Mycobacterium bovis</i> in a multi-host system.
Crispell Joseph J Benton Clare H CH Balaz Daniel D De Maio Nicola N Ahkmetova Assel A Allen Adrian A Biek Roman R Presho Eleanor L EL Dale James J Hewinson Glyn G Lycett Samantha J SJ Nunez-Garcia Javier J Skuce Robin A RA Trewby Hannah H Wilson Daniel J DJ Zadoks Ruth N RN Delahay Richard J RJ Kao Rowland Raymond RR
eLife 20191217
Quantifying pathogen transmission in multi-host systems is difficult, as exemplified in bovine tuberculosis (bTB) systems, but is crucial for control. The agent of bTB, <i>Mycobacterium bovis</i>, persists in cattle populations worldwide, often where potential wildlife reservoirs exist. However, the relative contribution of different host species to bTB persistence is generally unknown. In Britain, the role of badgers in infection persistence in cattle is highly contentious, despite decades of r ...[more]
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