Ontology highlight
ABSTRACT:
SUBMITTER: Fusciello M
PROVIDER: S-EPMC6917704 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Nature communications 20191217 1
Virus-based cancer vaccines are nowadays considered an interesting approach in the field of cancer immunotherapy, despite the observation that the majority of the immune responses they elicit are against the virus and not against the tumor. In contrast, targeting tumor associated antigens is effective, however the identification of these antigens remains challenging. Here, we describe ExtraCRAd, a multi-vaccination strategy focused on an oncolytic virus artificially wrapped with tumor cancer mem ...[more]