Ontology highlight
ABSTRACT:
SUBMITTER: Lehner C
PROVIDER: S-EPMC6918766 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Lehner Christine C Spitzer Gabriel G Gehwolf Renate R Wagner Andrea A Weissenbacher Nadja N Deininger Christian C Emmanuel Katja K Wichlas Florian F Tempfer Herbert H Traweger Andreas A
Disease models & mechanisms 20191216 12
Tendon disorders frequently occur and recent evidence has clearly implicated the presence of immune cells and inflammatory events during early tendinopathy. However, the origin and properties of these cells remain poorly defined. Therefore, the aim of this study was to determine the presence of cells in healthy rodent and human tendon tissue fulfilling macrophage-like functions. Using various transgenic reporter mouse models, we demonstrate the presence of tendon-resident cells in the dense matr ...[more]