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Association between localised retinal nerve fibre layer defects and cardiovascular risk factors.

ABSTRACT: Localised retinal nerve fibre layer defects (RNFLDs) are reported to indicate the degree of glaucomatous damage but can also be sequelae of retinal vascular insufficiency as a result of systemic vascular factors. We investigated the association between RNFLDs and cardiovascular risk factors. RNFLDs were detected in 440 (29.2%) of 1508 subjects. The presence of RNFLDs was associated with higher HbA1c (odds ratio [OR] 1.289, p?

SUBMITTER: Shin JY 

PROVIDER: S-EPMC6920147 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

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Association between localised retinal nerve fibre layer defects and cardiovascular risk factors.

Shin Joo Youn JY   Lee Jonghyun J   Lee Chan Joo CJ   Park Sungha S   Byeon Suk Ho SH  

Scientific reports 20191218 1

Localised retinal nerve fibre layer defects (RNFLDs) are reported to indicate the degree of glaucomatous damage but can also be sequelae of retinal vascular insufficiency as a result of systemic vascular factors. We investigated the association between RNFLDs and cardiovascular risk factors. RNFLDs were detected in 440 (29.2%) of 1508 subjects. The presence of RNFLDs was associated with higher HbA<sub>1c</sub> (odds ratio [OR] 1.289, p < 0.001), higher 24-h mean systolic blood pressure (SBP; OR  ...[more]

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