Ontology highlight
ABSTRACT:
SUBMITTER: Galisteo Pretel A
PROVIDER: S-EPMC6921050 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Galisteo Pretel Alberto A Pérez Del Pulgar Helena H Olmeda A Sonia AS Gonzalez-Coloma Azucena A Barrero Alejandro F AF Quílez Del Moral José Francisco JF
Biomolecules 20191116 11
Naturally occurring nootkatone, with reported insecticidal and acaricidal properties, has been used as a lead to generate molecular diversity and, consequently, new insect antifeedant and ixodicidal compounds. A total of 22 derivatives were generated by subjecting this molecule to several reactions including dehydrogenation with the iodine/DMSO system, oxidation with SeO<sub>2</sub>, epoxidation with <i>m</i>CPBA, oxidation or carbon homologations of the α-carbonyl position with TMSOTf (trimethy ...[more]