Laser Doppler blood flowmeter as a useful instrument for the early detection of lower extremity peripheral arterial disease in hemodialysis patients: an observational study.

ABSTRACT:

Background

A simpler method for detecting atherosclerosis obliterans is required in the clinical setting. Laser Doppler flowmetry (LDF) is easy to perform and can accurately detect deterioration in skin perfusion. We performed LDF for hemodialysis patients to determine the correlations between blood flow in the lower limbs and peripheral arterial disease (PAD).

Methods

This retrospective study included 128 hemodialysis patients. Patients were categorized into the non-PAD group (n?=?106) and PAD group (n?=?22), 14 early stage PAD patients were included in the PAD group. We conducted LDF for the plantar area and dorsal area of the foot and examined skin perfusion pressure (SPP) during dialysis.

Results

SPP-Dorsal Area values were 82.1?±?22.0?mmHg in the non-PAD, and 59.1?±?20.3?mmHg in PAD group, respectively (p?ConclusionLDF is a simple technique for sensitive detection of early-stage PAD. This assessment will help physicians identify early-stage PAD, including Fontaine stage II in clinical practice, thereby allowing prompt treatment.

SUBMITTER: Ishii T 

PROVIDER: S-EPMC6921472 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature