Ontology highlight
ABSTRACT:
SUBMITTER: Sakellaridi S
PROVIDER: S-EPMC6922088 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Sakellaridi Sofia S Christopoulos Vassilios N VN Aflalo Tyson T Pejsa Kelsie W KW Rosario Emily R ER Ouellette Debra D Pouratian Nader N Andersen Richard A RA
Neuron 20190307 3
Although animal studies provided significant insights in understanding the neural basis of learning and adaptation, they often cannot dissociate between different learning mechanisms due to the lack of verbal communication. To overcome this limitation, we examined the mechanisms of learning and its limits in a human intracortical brain-machine interface (BMI) paradigm. A tetraplegic participant controlled a 2D computer cursor by modulating single-neuron activity in the anterior intraparietal are ...[more]