Ontology highlight
ABSTRACT:
SUBMITTER: Nazarieh M
PROVIDER: S-EPMC6923402 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Nazarieh Maryam M Helms Volkhard V
Scientific reports 20191219 1
Putative disease-associated genes are often identified among those genes that are differentially expressed in disease and in normal conditions. This strategy typically yields thousands of genes. Gene prioritizing schemes boost the power of identifying the most promising disease-associated genes among such a set of candidates. We introduce here a novel system for prioritizing genes where a TF-miRNA co-regulatory network is constructed for the set of genes, while the ranks of the candidates are de ...[more]